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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
18.18
Human Site:
S353
Identified Species:
26.67
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
S353
G
S
Q
I
T
Q
Q
S
T
N
Q
S
R
N
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
S333
G
S
Q
I
T
Q
Q
S
T
N
Q
S
R
N
P
Dog
Lupus familis
XP_548446
534
59045
S515
G
S
Q
I
T
Q
Q
S
T
N
Q
S
R
N
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
S353
G
S
Q
I
T
Q
Q
S
T
N
Q
S
R
N
P
Rat
Rattus norvegicus
Q641Z4
372
42743
S353
G
S
Q
I
T
Q
Q
S
T
N
Q
S
R
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
A296
G
H
M
P
Q
Q
P
A
N
Q
S
R
N
P
A
Chicken
Gallus gallus
Q5ZKN1
372
42784
P353
G
G
H
M
P
Q
Q
P
A
N
Q
G
R
N
P
Frog
Xenopus laevis
Q4V862
376
43205
P357
G
G
H
M
P
Q
Q
P
A
N
Q
A
R
N
P
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
A375
G
H
M
P
Q
Q
P
A
N
Q
N
R
N
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
Q385
N
Q
M
R
N
Y
H
Q
Q
L
T
T
M
N
Q
Honey Bee
Apis mellifera
XP_396015
382
43973
H359
G
H
I
R
H
P
H
H
Q
V
P
G
G
P
A
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
Q451
H
A
N
R
G
R
H
Q
N
A
Q
Q
R
P
N
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
A382
Q
H
P
A
A
A
A
A
A
N
H
R
N
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
K363
R
Q
N
E
E
A
A
K
R
Q
K
L
Q
H
P
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
P404
Q
S
L
S
Q
R
V
P
T
A
P
R
G
H
I
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
K365
A
A
L
P
P
A
P
K
G
G
T
V
G
R
G
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
53.3
53.3
13.3
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
60
66.6
20
N.A.
13.3
6.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
7
7
19
13
19
19
13
0
7
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
63
13
0
0
7
0
0
0
7
7
0
13
19
0
7
% G
% His:
7
25
13
0
7
0
19
7
0
0
7
0
0
13
7
% H
% Ile:
0
0
7
32
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
13
0
0
7
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
0
0
0
7
0
7
0
0
0
% L
% Met:
0
0
19
13
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
0
13
0
7
0
0
0
19
50
7
0
19
50
7
% N
% Pro:
0
0
7
19
19
7
19
19
0
0
13
0
0
32
50
% P
% Gln:
13
13
32
0
19
57
44
13
13
19
50
7
7
0
7
% Q
% Arg:
7
0
0
19
0
13
0
0
7
0
0
25
50
7
0
% R
% Ser:
0
38
0
7
0
0
0
32
0
0
7
32
0
0
0
% S
% Thr:
0
0
0
0
32
0
0
0
38
0
13
7
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _